Types of Hodgkin Lymphoma
There are two main and distinct cancers called: classical Hodgkin lymphoma and nodular lymphocyte predominant Hodgkin lymphoma. Classical Hodgkin lymphoma consists of nodular sclerosis, mixed cellularity, lymphocyte-rich and lymphocyte depleted subtypes. There are also a few patients where the cells do not ‘fit in’ to any of these subtypes. These are then considered to be Hodgkin lymphoma unclassifiable. Each type of lymphoma is described here:
1. Classical Hodgkin Lymphoma
- 60 to 80% of patients have this type of Hodgkin lymphoma
- More commonly seen in young adults
- Usually involves the lymph glands of the neck and chest.
- 15 to 30% of patients have this type of Hodgkin lymphoma
- More commonly seen in people over 50 years.
- About 5% of patients have this type of Hodgkin lymphoma
- Usually diagnosed at an early stage in adults (40 to 50 years).
- Less than 1% of patients have this type of Hodgkin lymphoma
- Tends to be more widespread at diagnosis
- More common in older patients and in non-industrialized countries
- More common in HIV-positive patients.
2. Nodular Lymphocyte Predominant
- Tends to be slow growing.
Most patients respond well to treatment regardless of the type of Hodgkin lymphoma they have. A more important consideration in the choice of treatment is how widely the lymphoma has spread in your body (i.e., the stage of the disease).